bioXEN graft, from Ousia, is an anorganic natural bone mineral, produced by the removal of material from bovine cancellous bone.
bioXEN graft, from Ousia, is an anorganic natural bone mineral, produced by the removal of material from bovine cancellous bone. It compares to BioOss ® It is a safe and biocompatible osteoconductive material that can be used a graft material to aid bone formation in oral defects.
The manufacturing process for bioXEN allows for a combination of a porous structure for vascular access with a roughened surface that is favorable to cell adhesion and subsequent bone matrix deposition. Ousia bioXEN allows the clinician to have available a safe and biocompatible osteoconductive matrix that can be used for new bone formation in defects.
bioXEN and BioOss® sections taken at 2 months, show residual implant material present within the defects. The histology images shown below refer to new bone in apposition to the bioXEN or Bio-Oss® bone mineral matrix. New bone (green) can also be seen adjacent to the mineral showing evidence of ongoing bone formation in the defect area.
In vivo studies comparing Ousia bioXEN and Bio-Oss®, show the similarities in performance of these products. In this study, there were no significant differences between the two products. (2)
1\. Bio-Oss® is a registered trademark of Geistlich, Wolhusen, Switzerland.
2. Data on file.