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Osteocel: Eliminate Need for an AutoGraft Due to Unique Properties?

posted in Bone Grafting, Tissue Regeneration, en

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Dr. U. asks:
I have seen advertisements for Osteocel [Ace Surgical Supply] which describe this as a bone matrix product containing stem cells. It is supposed to be osteoconductive, osteoinductive and osteogenic. This should eliminate the need for an autograft because of its unique properties. Has anybody tried this and does it do what the manufacturer claims? Is it economically affordable for routine use for bone augmentation procedures? Has anybody tried this in a maxillary sinus lift procedure?

4 Responses to “ Osteocel: Eliminate Need for an AutoGraft Due to Unique Properties? ”

• Charles Schlesinger, DDS July 27th, 2009

  
  

  Osteocel shows some great promise. Is it a replacement for a block graft? Well, depends on what you are trying to accomplish and how you go about doing it. You use a block graft when you a solid piece of bone that will turnover slowly and resist compression by the soft tissue and occasional masticatory forces. If you place Osteocel and use a tenting screw and a membrane or use a Ti reinforced membrane- yes it can be used in sites where we would normally block graft.

  The other advantage of Osteocel is the concentration of stem cells in the product. When compared to PRP is it pretty amazing. PRP will provide about 5k cells/cc, where the 1st generation of Osteocel had 50k cells/cc and the newest version is reported to have up to 250k cells/cc. So is it osteoconductive,inductive and promotive- yes!

  The other cool thing about it is you can extend it with your particulate of choice up to 50%. That makes teh cost for 1cc very good. I believe it is about $650/cc for the product which makes it much more affordable than BMP(Infuse).

• Andrew W Kelly DDS July 28th, 2009

  
  

  I have been using the product for about 2 years now. It works very well. Not only does it cause robust bone growth it also effects wonderful soft tissue healing. i believe that within 5 years products like this will replace most autogenous bone grafts.

• David Levitt August 5th, 2009

  
  

  I just re-entered my first two osteocel sites, both mandibular distal extension lateral augmentations. The results were nothing short of spectacular. There was no loss whatsoever of graft height or width. I did use a resorbable membrane (Ace RCM) and tacks to contain the graft. I have now placed implants in each site. The only prblem I had was the bone was so hard I had trouble drilling the osteotomies. I’m sold on this material from what I have seen so far.

• Dr. C August 6th, 2009

  
  

  I am interested in using Osteocel. Can you guys tell me if you used it in conjuction with another material (FDBA etc) or by itself? How much lateral augmentataion have you been able to achieve (4,5,6mm)?

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