Bondbone (calcium sulfate alloplast) washing out: thoughts?

I attempted a socket preservation procedure using a calcium sulfate alloplast [Bondbone, MIS] after extraction of #10 root [maxillary left lateral incisor; 22]. The extraction was atraumatic and uneventful and I thoroughly debrided the socket and irrigated copiously with sterile saline. Bondbone was placed in accordance with the manufacturer’s instructions, and the site was sutured but not closed completely. On recall 1 week after, most of the Bondbone material had washed out. Have any others had this issue? I understand by not closing the site its more prone to washing out, etc., but as I understand it, it is not a requirement with using Bondbone? Any thoughts?

17 Comments on Bondbone (calcium sulfate alloplast) washing out: thoughts?

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Peter Fairbairn
2/6/2013
Whilst Bond Bone is a very good CaSO4 one has to be cautious about the manufacturers blurb , " Bi-phasic etc " it needs to be used in the manner that CaSO4 s are as an particulate "bonder" or a membrane. Mixing the hemi-hydrate with the di-hyrate component helps it to set but does not make it bi-phasic and thus when used in your situation ( socket graft ) needs to be mixed with a BTcP or highly porous HA synthetic graft material as patient dependant it will bio-absorb too rapidly thus not providing a scaffold for bone formation. Anther tip is to let the site heal for 3 weeeks then graft as you would have some soft tissue closure to reduce wash out. Peter
Sb oms
2/6/2013
This is why I use a membrane on every socket graft I do. I don't rely on setting materials. Additionally, the mouth is a wild place. Who knows what your patients do with their tongue after they leave your office.
CRS
2/9/2013
I agree I 've had patients pick out their connective tissue grafts with toothpicks! They play with their surgical flaps while they are sitting in the chair talking to you!
CRS
2/8/2013
I have used synthetics in areas the implant placement is not critical, even when allografts are used if packed too densely you get good space maintenance but less quality bone. In an esthetic area my materials of choice are allograft with an esthetic primary closure or a Teflon membrane to get guided tissue. You get a great result. Remember that the lateral incisor area is thin and difficult to restore, often a connective tissue graft is often necessary for esthetics. This graft will have to be redone, I let the wound granulate in, open a flap and restore as above seeing how much buccal plate collapse you have. I don't understand he rationale for using a synthetic in this esthetic area. I feel that the practioner has to use discretion in selection of restorative materials based on result not ease of placement or cost. I often hav to redo these type of cases but I don't want to offend my referring doctors ( general and specialists) work. Believe me I have had failures and had to do revisions so please don't take this as a criticism just sharing my experience. Good luck
greg steiner
2/8/2013
Calcium sulfate will never set in an extraction site. Calcium sulfate is water soluble and needs to be dehydrated for set to occur and this never happens in an extraction socket. Greg Steiner Steiner Laboratories
Peter Fairbairn
2/9/2013
After 10 years and 1,500 synthetic grafts without the use of a traditional membrane I feel I am beginning to understand concepts that are utilised by our Orthopedic friends.Greg you can get CaSo4 to set which we showed in research at the EAO last year although I generally use poly lactide coated BTcP products where obvoiusly soft tissue closure cannot be achieved.. Technique is everything I routinely place implants in large defects sometimes even without primary stability and load at 10 weeks . The body wants to heal if we work with it. We have cores , micro CT even Synchrotron CT studies. Interesting area , as I say sometimes just because I cannot climb it does not mean that it cannot be done. Peter
CRS
2/10/2013
Very interesting analogy, food for thought. In orthopedics it is a bit different, I remember when hip replacements were stabilized with poly methyl methacrylate and the or suite smelled like dental school, we'd get questions from the ortho residents! If this can work, yes the body can heal itself. The differences are that orthopedic procedures are sterile, dental cases are clean. Ortho cases are closed and not subject to oral stresses and it is a different bone type. Long bone vs membranous. However I actually think that the orthopods have borrowed from dental and the same osteointegration techniques apply. I think that in orthopedics and in skull defects the synthetics are good but one must remember that the orthopods are not going to be placing a dental implant subject to the oral flora in theses regenerated synthetics. That said I use orthopedic products in my dental implant cases used in spinal surgery. It is quite amazing how the specialties can benefit each other!
Richard Hughes, DDS, FAAI
2/10/2013
Peter, thank you.
OMFS
2/11/2013
Peter uses Infuse
Peter Fairbairn
2/12/2013
Dear OMFS , stiil banned here in Europe ,maybe wisely..... Do not really need it anyway, I prefer not to cross species any work on my patients. Regards Peter
Richard Hughes, DDS, FAAI
2/12/2013
Infuse -----a bit expensive, yields very soft bone and the inflammatory reaction can have serious consequences. The bond bone most likely washed out because the patient did not follow post op instructions or it was poorly contained. When using any graft material, the patients marrow blood has to be incorporated.
greg steiner
2/12/2013
Peter If you can get pure calcium sulfate to set in an extraction site you are defying the laws of chemistry. Calcium sulfate has a high Ksp and will not participate unless dehydrated after mixing. If you put mixed calcium sulfate in a closed container it will never set. An extraction site is a closed container infused with water. We use calcium sulfate in the lab and in the clinic when we want something to wash out in physiologic conditions. If you are modifying calcium sulfate or adding something to it to get it to set then it is not calcium sulfate. I would enjoy seeing the cited research. Aloha Greg Steiner Steiner Laboraotires
Jim
2/27/2013
BondBone is unlike the hemi-hydrate calcium sulfate that is commonly seen. It will set in the presence of blood and saliva due to the biphasic nature of the product. You can leave it exposed but I would recommend using some type of barrier between the product and the oral environment. Using a collagen plug, Cytoplast membrane or cyanoacrylate tissue cement will protect the graft while the soft tissue closes over it during the initial weeks of healing. Placing sutures over the site will also speed the healing time as well.
Peter Fairbairn
2/13/2013
Hi Greg as you know Bond Bone is a mixture of Hemi and Di-hydrate which appears to help in this setting where there is generally an excess of blood . This as you know can be achieved with "normal" CaSO4 by using some and mixing it into you second mix which is in fact what BB is. I will send you the research we did when I get back from the US next week . Regards Peter
greg steiner
2/13/2013
Peter If I understand the way to get calcium sulfate to set in an extraction socket is to mix it up and have it set then mix up the set calcium sulfate particles with hydrated calcium sulfate and in the socket the dried calcium sulfate particles suck out the water from the hydrated calcium sulfate and it sets. If a dry extraction socket I can see how that would work but the mixture is still water soluble and any bleeding will prevent setting. I look forward to your research and the weather here has been a bit cold lately with the temps at night down into the high 60's. Aloha Greg
Peter Fairbairn
2/13/2013
Hi Greg , agreed on the mixing as that is what I do daily and that is what I warned the poster about. You are in an enviable position in Hawaii as weather not great. Regards Peter
greg steiner
2/13/2013
Any graft material can wash out if exposed to the oral environment. To solve this problem for our grafts we developed Socket Seals and they should solve the problem you are having with calcium sulfate. Greg Steiner Steiner Laboratories

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