Thanks Phil for pointing us to this great paper by Kim. There are many more papers that have looked at this topic and the success of using dentin graft. One of the key observations is how well it is accepted by the patient's own body, the fact that the fresh autologous dentin attracts progenitor cells at the site, the fact that inflammation and adverse reactions are rarely observed (due to it being autologous), the fact that the dentin graft undergoes immediate ankylosis with the opposed bone and therefore stabilizes the site and the fact that the histology shows a very fine cementum line and no granulation tissue - all results of utilizing an autologous graft vs grafts that are either synthetic or heavily processed from same species or other species that simply lost most of their biological properties and in some cases could introduce disease transmission.
I agree that bone and tooth are not the same, but they are almost identical. It's like saying that a wood table and a wood chair are not the same, but when you grind them up, you end up with wood pulp. This is too simplistic - I know. So if we look at the makeup of cortical bone we get 60% of Crystalline Calcium Phosphate or HA, 30% Collagen Type I, and 10% water. Yes there's a little bit of BMP and even some stem cells. When you look at a tooth including all its components (dentin, enamel, pulp,...) we get approximately 70% Crystalline Calcium Phosphate or HA, 25% Collagen Type I, and 5% water, BMPs, and yes, even stem cells. In fact, there are more BMPs in a tooth than there are in bone - which is a very good thing if you're using it as a graft. So bone and tooth are not the same, but they are almost identical after they are grounded up. We have been using autologous dentin grafts for over 6 years now and the results are predictable - long lasting bone maintenance with very little recession if any. I'm glad that more and more dentists are taking to it for optimizing results for their patients.
That's great information that I wasn't aware of. Thank you Amit!