An Alternative to Bone Grafting?

Any thoughts on Medtronic’s Infuse product which an FDA panel recently recommended for approval to help regrow bone in adults to provide an anchor for dental implants?

Infuse is a collagen sponge impregnated with a human bone growth factor. It is already approved for use in certain lower back procedures and treating some forms of severe leg fractures.

Medtronic wants to market Infuse as an alternative to bone grafting, which the company says is equally effective, but requires surgeons to take bone from elsewhere in the body to anchor a dental device in the mouth. However, experts complained that Medtronic did not sufficiently test Infuse in tooth extraction sockets.

“The data submitted is not rigorous enough,” said Janine Janosky, an assistant professor of biostatistics at the University of Pittsburgh and a member of the panel. Dr. Patters an FDA panel member and a professor of periodontology at
the University of Tennessee, said that bone grafts like the ones Infuse is meant to replace are not generally performed in tooth extraction patients, limiting Infuse’s attractiveness as an alternative to grafting surgeries for those patients.

The FDA panel of outside
experts recommended Infuse’s label highlight that it has not
been tested in molar extraction sites, or in the lower jaw,
where the majority of tooth extractions occur.



2 thoughts on “An Alternative to Bone Grafting?

  1. Bob Horowitz says:

    As we have read, there have been many, as of yet, unsubstantiated promises regarding BMP’s and other growth factors. If we read the literature carefully, there are a number of biologically PROVEN ways to get very high percentages of vital bone in augmented sites without the use of expensive, untested (in many human applications) growth factors.

    (0)

Comments are closed.

Posted in Clinical Questions, Regenerative.
Bookmark An Alternative to Bone Grafting?

Videos to Watch:

Lateral Sinus Lift: Perforation, Repair, and Implants

These two videos demonstrate the lateral window sinus technique, and implant placement following the repair[...]

Watch Now!
Single Tooth Replacement with Implants in the Esthetic Zone

Dr. Jack Hahn provides tips and reviews cases for implant placement in the esthetic zone.[...]

Watch Now!
Surgical Consideration for the Flapless Approach

In this video, Dr. Jack Hahn discusses and presents cases to review the surgical considerations[...]

Watch Now!
Bond Apatite: Socket Preservation Cases

These 2 videos show the use of Bond Apatite in socket preservation cases, one with[...]

Watch Now!
3D Guided Implant Placement

The placement of multiple implants in this case was helped thru the use of 3d[...]

Watch Now!
Ridge Splitting Cases in Narrow Alveolar ridge

This videos shows ridge splitting, which when combined with bone expansion, is an effective technique[...]

Watch Now!
Placement of 4 Implants and Cement-Retained Bridge

The treatment plan was to extract the lower incisors, canines, and lower premolar and place[...]

Watch Now!
Failing Bridge Replaced with Dental Implant Supported Bridge

Ahe patient presented with a failed dental bridge from the upper right canine to the[...]

Watch Now!
Lateral Sinus Augmentation with CGF

Following membrane elevation with the lateral approach, and confirmation of an intact sinus membrane, concentrated[...]

Watch Now!
Titanium Mesh for Ridge Augmentation

The use of titanium mesh is a reliable method for ridge augmentation to provide adequate[...]

2 Comments

Watch Now!
Implant Grafting Techniques: Demineralized Sponge Strip and Tunneling

This video reviews several unique grafting and surgical techniques, including the use of demineralized cancellous[...]

Watch Now!
Mandibular Fixed Screw Retained Restoration

This video shows the use of a surgical guide for a mandibular fixed screw retained[...]

1 Comment

Watch Now!