Dental implants in a young patient on Remicade infusions for cervical spondylitis?

I have a 39 year old male, non-smoker, with cervical spondylosis who gets an infusion of infliximab (Remicaide) every 6 weeks.  He is not taking methotrexate or a steroid.  I have recently extracted #30 and #19.  Both had failed root canal treatment and vertical fractures.  I am planning on inserting an implant in each site.  Does anyone have any recommendations on how to proceed?  Should we stop infliximab (remicaide) 1 month prior to implant insertion or does it not matter?  Will this have a significant influence on osseointegration?

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4 thoughts on “Dental implants in a young patient on Remicade infusions for cervical spondylitis?

  1. The recommendation is to forget implants. Remicaid is not a friend of bone healing. They will fail–and this bone is already quite sick. Implant success absent Remicaid would still be quite iffy here!. Even then the sites Would need at least a year to heal.

  2. Thanks Doc for your encouraging comments. Besides immunosuppression, Remicade has little other effect on humans. But I will tread with caution.
    Any other input from anyone else?
    -Dr. VS

  3. Remicade will have little effect on integration and may actually improve bone metabolism. If the extraction site heals within normal limits I would have no problem placing an implant in this patient. Here is a study that supports improved bone metabolism with Remicade therapy.
    Eur J Gastroenterol Hepatol. 2016 Nov;28(11):1335-44. doi: 10.1097/MEG.0000000000000719.
    A 1-year prospective study of the effect of infliximab on bone metabolism in inflammatory bowel disease patients.

    Greg Steiner Steiner Biotechnology

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