Doxycycline with bone graft for lateral sinus lift?

Last Updated: Aug 15, 2018

Have any of you used doxycycline with bone graft for a lateral sinus lift? If so what was the doxycycline to graft ratio? To my knowledge doxycycline is acidic. Ä°f too much is used does it dissolve the bone graft or harm the sinus membrane and host bone?

4 Comments on Doxycycline with bone graft for lateral sinus lift?

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DrG

08/15/2018

What would be the purpose of the doxycycline? There is no clinical data to support its use in a sinus lift.

dr.alpertufan

08/17/2018

There is some study in the literature about using tetracyclines combined with bone grafts. I havenâ€™t find any study about using it in sinus lifting but It is already being used

Greg Kammeyer, DDS, MS

08/15/2018

Since it is a broad spectrum, bacteriostatic drug it would have low efficacy. If you want to mix something into your lateral window sinus grafts use L-PRF to up regulate VEG-F (increasing angiogenisis) or Clindamycin to bacteriocidal for anerobes. Personally I use L-PRF with PDGF as the PDGF cuts the waiting down to 3-4 months instead of 6-8 months.

Dan

08/16/2018

I'm using RIFAMYCIN . good results.

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