BonMaker: Using a Patient’s Own Teeth for Bone Graft?

This product seems interesting, but of course it requires alot more testing and I agree that I'm not quite sure it's viable economically-speaking for the US market, which has ample supply of tissue banks for allografts. However, in other places in the world where allograft from tissue banks is not used or is illegal, I guess this product has potential. But, the safety needs to be more guaranteed, which will only come with more time and use. That said, to ask for studies of a bone graft product is a bit facetious. I do not believe there are any statistically viable human studies (i.e. large enough study sample with controls etc.) regarding any dental bone graft product on the market, whether allograft, xenograft, or synthetic bone products. Most studies are just done using animals or very small human samples with no adequate control groups and any other basic study design principles. If there are any large scale human studies for bone grafting in dentistry, I'd love to see them. I am willing to bet that not one large scale human study of materials used in dentistry for bone grafting, if it even exists, would past muster with the FDA in terms of showing proven efficacy. Basically, the reality is that dentists just use what experience has shown them to be safe and to work, even if there are no viable studies to support any material and absolutely no real biological understanding of how bone regeneration actually occurs with these products. So this notion of needing studies is a straw man argument. Also, since this point was mentioned above by another commentator, the idea that any of the products currently out there are more than just osteoconductive is purely speculative. The only material that is proven to be both osteoconductive and osteoinductive is an autograft. Nearly everything else we use (PRF, could be an exception) is really just osteoconductive. The fact of the matter is you can put plaster of paris in a patient's mouth (and many dentists do, it's just marketed under a fancier name so nobody thinks of it as plaster of paris), and you'll get good bone regeneration. So, it's not far fetched to assume that using a patient's own teeth, properly treated and disinfected, will regnerate bone. I'd go far as to say that I'd be surprised if a patient's own teeth didn't have good regenerative properties, or work at least as well as the many other foreign materials we place in patient's mouth now to regenerate bone. Bone regeneration is very poorly understand on a theoritical level, and practically speaking it remains an art of just using what we know is safe and seems to have worked in the past.