Patient with Thalassemia Minor: Contraindication for Dental Implants?

Dr. SM, an oral surgeon, asks:
In my practice I am referred patients with medical complications for placement of dental implants. In many cases the placement of the implant itself is relatively simple but the management of the medical issues is complex and often difficult. Nearly all of these patients are high risk. I recently was referred a patient with Thalassemia Minor – the mild form of Thalassemia. Are there any contraindications to placing dental implants in these patients? Are there any special precautions that I should take? Is there a decreased chance of success?

Editor’s Note: From Wikipedia – “Thalassaemia or “thalassemia” is an inherited autosomal recessive blood disease. In thalassemia, the genetic defect results in reduced rate of synthesis of one of the globin chains that make up hemoglobin. Reduced synthesis of one of the globin chains can cause the formation of abnormal hemoglobin molecules, thus causing anemia, the characteristic presenting symptom of the thalassemias.”

2 Comments on Patient with Thalassemia Minor: Contraindication for Dental Implants?

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Dr. C
5/11/2010
Misch CM, Jolly RL, Williams DR, Chorazy CJ. Maxillary implant surgery on a patient with thalassemia: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;86:401-405.
K. Moore
5/25/2010
It is unlikeley that your patient has Beta Thal Major (Cooley's anemia)- this usually leads to early death (before age 20). The genetic mutations present in β thalassemias are very diverse: both deletions and nondeletions occur... The Thal Minor variant should pose no problems (is it Beta Thal minor or intermedia?), although anemia can be an issue... Thalassemia intermedia patients vary a lot in their treatment needs, depending on the severity of their anemia. All thalassemia patients are susceptible to health complications that involve the spleen (which is often enlarged and frequently removed) and gall stones. These complications are mostly prevalent to thalassemia major and intermedia patients. Thalassemia minor, although not life threatening on its own, can affect quality of life due to the effects of a mild to moderate anemia. Hope this helps...

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